Stem Cell
Regenerative Biology is the Morgridge Institute's inaugural platform for realizing the institute’s discovery to delivery paradigm. In 2008, world-renowned stem cell pioneer and scientist Dr. James Thomson was appointed as its director and the first member of the Morgridge Institute’s multidisciplinary leadership team. This announcement signaled the institute’s commitment to recruiting world-class scientific talent to guide its mission of facilitating breakthrough research to improve human health.

Selected Publications


Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, Antosiewicz-Bourget J, O’Malley R, Castanon R, Downes M, Yu R, Stewart R, Ren B, Thomson JA, Evans RM,Ecker JR.
“Hotspots of aberrant epigenomic reprogramming in human iPS cells.” Nature (2011). 471(7336): 68-73. [PubMed]

Gore A, Li Z, Fung H, Young J, Agarwal S, Antosiewicz-Bourget J, Canto I, Israel M, Kiskinis E, Lee J, Loh Y, Manos PD, Montserrat N, Wilbert M, Yu J, Kirkness E, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LSB, Zhang K. “Somatic coding mutations in human induced pluripotent stem cells.” Nature (2011). 471: 63-71 [PubMed]

Yu P, Pan G, Yu J, Thomson JA.
“FGF2 sustains NANOG and switches BMP4 induced human ES cell differentiation from trophoblast to mesendoderm.” Cell Stem Cell (2011): 8: 326-334 [PubMed]


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