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September 29 - 30, 2011 | Wisconsin Institutes for Discovery | Town Center

DAY 1: Thursday, September 29, 2011
Time	Presentations and Speakers
12:30 – 3:00 p.m.	Registration Table Open Sign up for Friday box lunches ($10 at the registration table)
1:00 – 1:15 p.m.	Day 1 Welcome Remarks Rock Mackie, Director, Medical Devices Area, Morgridge Institute for Research
1:15 – 2:30 p.m.	Scientific Modeling Overview This introductory session presents both mathematical and bioscience perspectives on modeling, and how they need to interact to advance scientific knowledge. Watch Video John Yin Professor of Chemical and Biological Engineering and Systems Biology Theme Leader, Wisconsin Institute for Discovery, UW–Madison Michael Ferris Professor of Computer Sciences and Optimization Theme Leader, Wisconsin Institute for Discovery, UW–Madison
2:30 – 3:30 p.m.	Short Talks: Current Research Projects Advanced by Modeling A series of presentations by UW–Madison faculty members will showcase research in different bioscience fields—all enabled by modeling approaches specifically suited to project goals. Moderator: Marisa Otegui Associate Professor of Botany and Faculty Affiliate, Laboratory of Cell and Molecular Biology, UW–Madison Speakers and Topics: Fariba Assadi-Porter Senior Scientist and Principal Investigator, Dept. of Biochemistry, UW–Madison "Metabolome Dynamics Platform (MDP): A Novel Method to Portray Metabolic Pathways for Early Disease Detection" Warren Porter Professor, Dept. of Zoology; Professor of Environmental Toxicology; and Invited Affiliate Faculty Member, Dept. of Engineering Physics, UW–Madison "Integrating Momentum, Heat and Mass Balances in Leatherback Sea Turtles: Body Size and Oceanic Distribution Consequences under Climate Change" Watch Video Sarah Duenwald-Kuehl Research Associate, Dept. of Orthopedics and Rehabilitation, UW–Madison "Mathematical Modeling of Tissue Damage and Healing Using FFT and Fractal Analyses" Watch Video Jennifer Reed Assistant Professor, Dept. of Chemical and Biological Engineering, UW–Madison “In Silico Design of Metabolic Networks” Watch Video Pamela Kreeger Assistant Professor, Dept. of Biomedical Engineering, UW–Madison "Multivariate Modeling to Predict Drug Sensitivity in Ovarian Cancer"
3:30 – 3:45 p.m.	Break
3:45 – 4:45 p.m.	Triad Panel 1: Radiation Modeling in Engineering Medicine Moderator: Carol Hirschmugl Professor of Physics, UW-Milwaukee and Honorary Fellow, Laboratory for Optical and Computational Instrumentation (LOCI), UW–Madison Panelists: Rock Mackie Director, Medical Devices Area, Morgridge Institute for Research Watch Video Soren Bentzen Program Leader, Imaging and Radiation Science Program, UW Carbone Cancer Center and Professor of Human Oncology, Medical Physics, Biostatistics & Medical Informatics, UWSMPH Watch Video Robert Jeraj Associate Professor of Medical Physics, UWSMPH Watch Video
4:45 – 5:00 p.m.	Poster Session Highlights A preview of select posters in the poster session that follows. Watch Video Moderator: Brenda Ogle Assistant Professor, Dept. of Biomedical Engineering, UW–Madison
5:00 – 6:00 p.m	Poster Session and Sponsor Tables Located in the first-floor atrium
5:00 – 6:00 p.m	Reception Located in the first-floor atrium and H.F. DeLuca Forum Reception sponsored by the Morgridge Institute for Research
6:00 – 7:00 p.m.	*Evening Keynote Address: "A Spectrum of Modeling Approaches for a Spectrum of Cell Biological Studies"* Doug Lauffenburger Ford Professor of Bioengineering and Professor, Depts. of Biological Engineering, Chemical Engineering and Biology, Massachusetts Institute of Technology Watch Video Introduced by: Sangtae Kim Executive Director, Morgridge Institute for Research Keynote sponsored by: Morgridge Institute for Research

DAY 2: Friday, September 30, 2011
Time	Presentations and Speakers
8:30 – 8:40 a.m.	Day 2 Welcome Remarks Ariel Fernandez Distinguished Investigator, Morgridge Institute for Research
8:40 – 9:30 a.m.	*Morning Keynote Address: "An Example of Mathematical Modeling in Biology - The Patterning of Butterflies"* Andy Wathen Reader in Numerical Analysis, Oxford University Mathematical Institute, UK and Sub-Warden of New College Introduced by: Amos Ron Professor, Depts. of Computer Sciences and Mathematics, UW–Madison Keynote sponsored by: Prairie Technologies
9:30 – 10:30 a.m.	Short Talks: Research Needs in Search of Modeling Solutions UW–Madison faculty members will present large-scale research problems that require modeling schemes or mathematical tools to clarify and organize data and findings. Moderator: Julie C. Mitchell Associate Professor, Depts. of Mathematics and Biochemistry, UW–Madison Speakers and Topics: Anna Huttenlocher Professor of Pediatrics, Medical Microbiology and Immunology, UW–Madison “Imaging Leukocyte Migration in Vivo” Watch Video Laurence Loewe Assistant Professor, Laboratory of Genetics and Wisconsin Institute for Discovery Systems Biology theme, UW–Madison "Evolutionary Systems Biology and Distributions of Mutational Effects" Watch Video Kurt Squire Creative Director, Morgridge Institute for Research Education Research Integration Area and Associate Professor, Dept. of Curriculum and Instruction, UW–Madison “Transforming Public Participation in Science With Technology” Watch Video Randolph S. Ashton Assistant Professor, Dept. of Biomedical Engineering, UW–Madison and Wisconsin Institute for Discovery BIONATES theme "A High-Throughput Platform for Investigating the Quantitative, Qualitative and Temporal Cues of the Stem Cell Niche.” Jon Audhya Assistant Professor, Dept. of Biomolecular Chemistry, UW–Madison "Mechanisms of Vesicle Scission" Watch Video
10:30 – 10:45 a.m.	Break
10:45 – 11:45 a.m.	Triad Panel 2: Real Time Problem Solving – Modeling of Breast Cancer Moderator: Lee Gravatt Wilke Associate Professor, Dept. of Surgery and Director, University of Wisconsin Health Breast Center, UW Health/UW School of Medicine and Public Health Panelists: Patricia Keely Professor, Dept. of Cell and Regenerative Biology, UW–Madison Alissa Weaver Associate Professor, Dept. of Cancer Biology, Vanderbilt University Medical Center Yi Jiang Technical Staff Member, Theoretical Division, Los Alamos National Laboratory and Associate Professor, Dept. of Mathematics & Statistics, Georgia State University Watch Video
11:45 a.m. – 1:00 p.m.	Lunch Attendees may order a $10 box lunch at Thursday's registration table; eat at Wisconsin Institutes for Discovery restaurants; or go to Union South or nearby eateries. Lunch is not provided as part of the MathBio3 format.
1:00 – 2:00 p.m.	Resource Panel: Careers in Scientific Modeling What are the job market and career pathways for scientific modeling expertise? What funding sources could help you integreate modeling approaches into cutting-edge research? This resource panel will provide answers. Moderator: Wendy Crone Professor, Dept. of Engineering Physics and Interim Associate Dean, Graduate School, UW–Madison Panelists: Andy Wathen Reader in Numerical Analysis, Oxford University Mathematical Institute, UK and Sub-Warden of New College Doug Lauffenburger Ford Professor of Bioengineering and Professor, Depts. of Biological Engineering, Chemical Engineering and Biology, Massachusetts Institute of Technology Curtis Rueden Software Architect, UW–Madison Laboratory for Optical and Computational Instrumentation (LOCI) Yi Jiang Technical Staff Member, Theoretical Division, Los Alamos National Laboratory and Associate Professor, Dept. of Mathematics & Statistics, Georgia State University Watch Video
2:00 – 3:00 p.m.	Afternoon Keynote Address: "Monte Carlo Simulation of Light Transport in Biological Tissues Steven L. Jacques Professor, Depts. of Dermatology and Biomedical Engineering, Oregon Health & Science University Introduced by: Sangtae Kim Executive Director, Morgridge Institute for Research Keynote sponsored by: Prairie Technologies Watch Video
3:00 – 4:00 p.m.	Short Talks: Effective Tools for Scientific Modeling Presentations by UW–Madison and affiliated experts will identify a range of modeling approaches, including mathematical tools, which can be used to accelerate and explain scientific research. Moderator: Miron Livny Chief Technology Officer, Morgridge Institute for Research and Professor, Dept. of Computer Sciences, UW–Madison Speakers and Topics: Dan Negrut Associate Professor, Nvidia CUDA Fellow, Dept. of Mechanical Engineering, UW–Madison "HCT: A Heterogeneous Computing Template for Dynamical System Simulation in Engineering" Watch Video Sushmita Roy Postdoctoral Fellow, Broad Institute, Harvard and MIT and Assistant Professor, Dept. of Biostatistics and Medical Informatics, UW–Madison and Wisconsin Institute for Discovery (starting Jan 2012) "Comparative Inference of Regulatory Programs of Stress Response" Dave Anderson Assistant Professor, Dept. of Mathematics, UW–Madison "The Computational Benefits of Using Random Time Change Representations for Stochastically Modeled Biochemical Reaction Networks" Watch Video Mark Craven Professor, Dept. of Biostatistics and Medical Informatics, UW–Madison, “Identifying Candidate Pathways to Explain Phenotypes in Genome-Wide Mutant Screens” Watch Video James B. Rawlings Professor, Dept. of Chemical and Biological Engineering, UW–Madison "Scientific Computing and Reproducible Computational Research Using GNU Octave" Watch Video
4:00 – 4:15 p.m.	Wrap of Sessions: Lessons Learned The wrap-up will summarize key themes of the symposium and provide an overview of further resources for scientific modeling, including recommended funding sources. Kevin Eliceiri Director, Laboratory for Optical and Computational Instrumentation (LOCI)