Our teaching labs located on the upper research floors of the Discovery Building offer many opportunities for researchers, the public and industry to explore science and try out scientific tools up close and hands on. Among these opportunities is a new equipment use program developed by WARF and the Morgridge Institute for Research.
 
Researchers and community members can sign up to try out the latest in scientific equipment, which is on loan to the teaching labs from various companies. Providing access to the newest and most advanced equipment is part of Discovery’s vision of ensuring that technology complements the work of researchers, the UW–Madison campus and private industry partners. 

In addition to microscopy capabilities, a full complement of cutting-edge molecular spectroscopy equipment now is available for use by the community. Training time and initial usage is provided free of charge, after which a fee structure applies. Please email the Lab Manager for details. To reserve these instruments, please apply below.

We want to hear from you! Please send any feedback you have about the program or the equipment you’d like to see to share@discovery.wisc.edu.

 

Scientific Equipment

 

Thermo Scientific DXR Raman Microscope

Technical Applications

  • Carbon Nanomaterials
  • Photovoltaics
  • Life Science Applications
  • Polymers and Packaging

Typical Customers

  • Research and Development
  • Analytical Laboratories
  • Materials Manufacturing
  • Pharmaceuticals

What Does It Do?

The DXR Raman microscope is a powerful tool for identifying unknowns, solving materials/chemical problems and characterizing structural changes. The DXR allows any user to walk up and take data quickly. Advanced features include patented autoexposure, an easy-to-use auto alignment tool and user upgradeable lasers, making this instrument ideal for a demanding, multi-user lab. Researchers are able to get immediate results and use the DXR’s automated quantification and library search routines to turn those results into answers.

How Does It Work?

Raman microscopy is capable of detecting sensitive changes in molecular bonds, with the added benefit of localizing the measurement to confined regions within a sample. Unlike IR microscopy, it can also be used with water-based samples. The DXR Raman microscope’s laser interacts with covalently bound molecules to produce a unique signature, or a kind of “molecular fingerprint.” This interaction returns reflected light with a slightly different wavelength, or color, that is detected by a very sensitive camera inside the instrument. The resulting spectrum is compared with standard references from known materials, allowing new and unknown substances to be quickly and reliably identified.

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Thermo Scientific Nicolet iS5 FT-IR Spectrometer

Technical Applications

  • Teaching Basic Chemistry
  • Incoming Materials Verification
  • Unknown Sample Identification

Typical Customers

  • Educational Teaching
  • Small Manufacturers
  • Forensic Drug Labs
  • QC Labs in many Industries

What Does It Do?

The Nicolet iS5 Fourier Transform Infrared (FT-IR) spectrometer integrates high-performance optics into a compact, rugged and reliable package. Its premium spectral performance and Award-winning OMNIC spectroscopy software make it an ideal tool for anyone needing a rapid and cost-effective solution for material verification, additive analysis, contaminant identification or structural elucidation.

How Does It Work?

Infrared spectroscopy takes advantage of the property of bonds within molecules to absorb infrared energy at unique wavelengths. The spectrum the instrument produces represents the sum of all the absorptions of light by the molecules in the sample being analyzed. The Nicolet iS5 FT-IR is optimized for data analysis in the mid-infrared region in the range from 2.5 to 25 micrometers (4000 – 400 wavenumbers), which is the region of primary vibrational frequencies for many chemical functional groups. Only bonds with a dipole moment will absorb infrared energy and create a spectrum. So for example, molecules like CO2 and H2O will have infrared spectra but symmetrical diatomic gases like H2, N22 or O2 will not.

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Thermo Scientific Evolution 220 UV-Visible Spectrophotometer

Technical Applications

  • Research and Development
  • Quality Assurance/Quality Control
  • Advanced Teaching

Typical Customers

  • Educational Research
  • Pharmaceutical/Biotech
  • Food and Beverage
  • Special Chemicals

What Does It Do?

Evolution 220 is an excellent choice to perform quantitative and qualitative analyses of a wide range of sample types by fixed wavelength, scan, quant and kinetic measurements with the help of comprehensive quantitative analysis solutions. The 2011 R&D Award winning instrument gives you the capability to perform your task with the assurance of reliable performance, the flexibility of customized options, and the convenience of achieving your goals.

How Does It Work?

In a UV-Visible spectroscopy, a sample is probed with photons of wavelength in the range of ultraviolet-visible light and absorbance is measured relative to an appropriate control. UV-Vis has immense analytical applications because analytes in mixtures that exclusively absorb photon radiation at particular wavelengths can be quantified independently of other components and an unknown material can be characterized by comparing with known materials. Solutions of transition metal ions, organic compounds with a high degree of conjugation, or those with alternating single and multiple bonds, and charge transfer complexes can be analyzed by UV-Vis spectroscopy.

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Thermo Scientific NanoDrop 2000c Spectrophotometer & NanoDrop 3300 Fluorospectrometer

Revolutionary Technology

Change the way you measure your nucleic acid and protein samples. Simply pipette 1–2 μL of the sample on the pedestal and measure. The sample is held in place by surface tension, generating a liquid column between the two optical fibers. In less than five seconds a full range spectrum is displayed along with the concentration and purity ratios. Wipe both pedestals and load the next sample with no carryover. Software modules guide you through routine UV-Visible and fluorescence measurements, including colorimetric protein analysis.

Technical Applications

  • Concentration and Purity Analysis of:
    • Nucleic Acids
    • Proteins
  • Fluorescence Emission & Labeling

Typical Customers

  • Life Science Research
  • Hospitals and Blood Banks
  • Biotech and Pharmaceutical
  • QA/QC in Manufacturing & Bioprocessing

What Makes the NanoDrop Unique?

NanoDrop 2000c: A xenon flash lamp light source fires through the sample vertically to acquire a full UV-Visible absorbance spectrum (190nm-840nm). The measurement pathlength adjusts automatically according to sample concentration. Changing pathlength in real time affords a large dynamic range, 2ng/μL to 15,000 ng/μL for dsDNA, essentially removing the need for dilutions. The low volume requirement appeals to researchers who work with small, precious samples and allows more frequent sample evaluation.

NanoDrop 3300: Three LED excitation sources that cover a broad wavelength range and allow the NanoDrop 3300 to measure a full emission spectrum from diverse fluorophores. Software includes pre-programmed methods for measuring a variety of common fluorophores, as well as a Method Editor, which provides the capability of building custom methods for applications like FRET and quenching.

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Be a Partner

The Shared Research Equipment Program brings your technology to the heart of campus. Our partners gain visibility, user feedback and potential customers. 

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